Integrin-binding peptides
US6177542A · kind A · utility
33Cited by
3References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 29, 1997 |
| Grant date | Jan 23, 2001 |
| Priority date | — |
| Expiry date | Aug 29, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides peptides having specificity for fibronectin-binding and vitronectin-binding integrins, and in particular for .alpha..sub.5.beta..sub.1 integrin. These peptides are characterized by having the ability to interfere with extracellular matrix protein binding to integrins; to block attachment of cells expressing these integrins to extracellular matrix proteins; and to promote cell attachment when coated onto a surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.