Patent · US Expired

Process for the synthesis of N-benzyl-3-(4-fluorophenyl)-1-4-oxazin-2-one

US6177564A · kind A · utility

1Cited by
3References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 9, 1999
Grant dateJan 23, 2001
Priority date
Expiry dateSep 9, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D265/32
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is concerned with a novel process for the preparation of N-benzyl-3-(4-fluorophenyl)-1,4-oxazin-2-one of the formula: ##STR1## This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particular, as substance P (neurokinin-1) receptor antagonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.