Membrane formed by an acrylonitrile-based polymer
US6180007A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 31, 1998 |
| Grant date | Jan 30, 2001 |
| Priority date | — |
| Expiry date | Jan 31, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2371/02
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A permselective graft polymer is disclosed that is formed by converting into intermediate reactive sites a portion of the cyano groups of a backbone polymer containing --CH.sub.2 --CH(--C.tbd.N)-- units, and grafting polyalkylene oxide polymer chains to the backbone polymer through the reactive sites. Either the backbone polymer of a polymer resin or a permselective polymer membrane can be grafted. When a resin is used, it is formed into a permselective polymer membrane using known methods. The resulting permselective membrane can be formed into hollow fibers or flat sheets for the encapsulation of living cells. The encapsulated cells are then implanted into a patient in need of the biologically active factors produced by the cells. The permselective graft polymer membrane exhibits good molecular diffusion with minimal protein adsorption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.