Patent · US Expired

Substituted pyrrolopyrimidines and processes for their preparation

US6180636A · kind A · utility

51Cited by
3References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 19, 1999
Grant dateJan 30, 2001
Priority date
Expiry dateFeb 19, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There are described 7H-pyrrolo[2,3-d]pyrimidine derivatives of the formula I ##STR1## in which the substituents are as defined in claim 1. These compounds inhibit the tyrosine kinase activity of the receptor for the epidermal growth factor (EGF) and c-erbB2 kinase and can be used as anti-tumor agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.