Patent · US Expired

Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein

US6180784A · kind A · utility

22Cited by
1References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 17, 1998
Grant dateJan 30, 2001
Priority date
Expiry dateJan 17, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/87
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides a process of transfecting a cell with a polynucleotide mixed with one or more amphipathic compounds and an effective amount of a DNA-binding protein. Exemplary and preferred DNA-binding proteins are H1, H2A, and H2B. Exemplary and preferred amphipathic compounds are cationic amphipathic compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.