Trangenic mice with a disruption in the tiar gene
US6180849A · kind A · utility
15Cited by
1References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 1998 |
| Grant date | Jan 30, 2001 |
| Priority date | — |
| Expiry date | Mar 17, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention features transgenic non-human mammals containing a mutation in one or both alleles of the endogenous TIAR gene, and cell lines derived from some of these mammals. The mammals and cell lines of the invention can be employed to identify compounds useful in treating infertility, obesity, neurological disorders, and ovarian sex cord stromal tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.