Transcobalamin mediated transport of vitamins B12 in intrinsic factor or receptor deficient patient
US6183723A · kind A · utility
11Cited by
0References
1Claims
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Key dates
| Filing date | Jan 21, 1998 |
| Grant date | Feb 6, 2001 |
| Priority date | — |
| Expiry date | Jan 21, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/714
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for oral treatment of patients using different types of drugs that are not usually transported to circulation, if administered orally, is disclosed. Because the TC II-Cbl complex is stable to acid and proteolytic enzymes both outside and inside the intestinal absorptive cells, the method consists of oral administration of a drug bound to TC II-Cbl complex. In addition, the method can also be used for delivering Cbl to a large number of patients who do not absorb Cbl due to a variety of causes such as surgery of their stomach (ulcers) or of their terminal ileum (Crohn's disease).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.