Subunit papilloma virus vaccine and peptides for use therein
US6183745A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jun 10, 1993 |
| Grant date | Feb 6, 2001 |
| Priority date | — |
| Expiry date | Jun 10, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a subunit papillomavirus vaccine which is protective against anogenital human Papillomavirus (HPV) infection. Peptides are also provided, which constitute an antigenic component of the vaccine. The peptide includes the sequence DRAHYNI (SEQ ID NO:11) and structural homologues thereof which concern a single amino acid substitution. The peptide is linked directly or indirectly to one or more amino acid sequences which correspond to a B epitope HPV16 and HPV18. The DRAHYNI (SEQ ID NO:11) sequence corresponds to a T helper epitope sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.