Patent · US Expired

Subunit papilloma virus vaccine and peptides for use therein

US6183745A · kind A · utility

16Cited by
0References
23Claims
0Family size

Assignees

Inventors

Key dates

Filing dateJun 10, 1993
Grant dateFeb 6, 2001
Priority date
Expiry dateJun 10, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2710/20034
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to a subunit papillomavirus vaccine which is protective against anogenital human Papillomavirus (HPV) infection. Peptides are also provided, which constitute an antigenic component of the vaccine. The peptide includes the sequence DRAHYNI (SEQ ID NO:11) and structural homologues thereof which concern a single amino acid substitution. The peptide is linked directly or indirectly to one or more amino acid sequences which correspond to a B epitope HPV16 and HPV18. The DRAHYNI (SEQ ID NO:11) sequence corresponds to a T helper epitope sequence.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.