Methods to identify compounds affecting mitochondria
US6183948A · kind A · utility
8Cited by
4References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1998 |
| Grant date | Feb 6, 2001 |
| Priority date | — |
| Expiry date | Apr 15, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5079
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for identifying a compound capable of modulating mitochondrial function, comprising contacting a eukaryotic cell with one or more candidate compounds, and detecting a change in the mitochondrial redox state of the cell. The methods further relates to such methods wherein endogenous fluorescence of the cell mitochondria is indicative of a change of redox state.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.