Method for reducing hook effect in an immunoassay

US6184042A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Ulrich Neumann · Peißenberg, DE
• Helmut Lenz · Tutzing, DE
• Norbert Franken · Starnberg, DE

Key dates

• Filing date: May 22, 1997
• Grant date: Feb 6, 2001
• Expiry date: May 22, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/962
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

In order to extend the measuring range and to reduce the Hook effect in an immunological method of determination of an antigen based on the principle of a sandwich assay it is preferable to use a method which is characterized in that the labelled detection molecule is an oligomer of a binding molecule selected from antibody or/and antibody fragment.