Composition and methods employing it for the treatment of 5-HT-mediated disorders
US6184219A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 9, 1999 |
| Grant date | Feb 6, 2001 |
| Priority date | — |
| Expiry date | Jul 9, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a composition comprising a first component (a) which is (R)-5-carbamoyl-8-fluoro-3-N,N-dicyclobutylamino-3,4-dihydro-2H-1-benzopyr an in the form of the free base, or a pharmaceutically acceptable salt and/or solvate thereof, and a second component (b) which is (+)-1-[3-(dimethylamino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile in the form of the free base, or a pharmaceutically acceptable salt and/or solvate thereof. The invention is further directed to the preparation of the composition, pharmaceutical formulations containing said composition, and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition, as well as a kit containing said composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.