Reverse-turn mimetics and methods relating thereto
US6184223A · kind A · utility
33Cited by
2References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1999 |
| Grant date | Feb 6, 2001 |
| Priority date | — |
| Expiry date | Jun 25, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility in the treatment of cell adhesion-indicated diseases, such as multiple sclerosis, atherosclerosis, asthma and inflammatory bowel disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.