Patent · US Expired

Substituted pyridine compounds and methods of use

US6184237A · kind A · utility

5Cited by
22References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 1, 1999
Grant dateFeb 6, 2001
Priority date
Expiry dateNov 1, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF-.alpha., IL-1.beta., IL-6 and/or IL-8 mediated diseases, and other maladies, suchas pain and diabetes. The inventin encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving inflammation, pain, diabetes, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermedates useful in such processes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.