Patent · US Expired

C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases

US6184244A · kind A · utility

22Cited by
3References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 30, 1999
Grant dateFeb 6, 2001
Priority date
Expiry dateJun 30, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention is directed to novel (N-substituted) indole ICE/ced-3-inhibitor compounds. The invention is also directed to pharmaceutical compositions of such indole compounds, plus the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.