Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension

US6184250A · kind A · utility

Assignee

• Alcon Laboratories, Inc. · US

Inventors

• Peter G. Klimko · Fort Worth, US
• John E. Bishop · Arlington, US
• Verney L. Sallee · Burleson, US
• Paul W. Zinke · Fort Worth, US
• Tom Dean · Cambridge, GB
• George Barnes · Arlington, US
• Michael L. Chandler · Crowley, US

Key dates

• Filing date: Mar 30, 1999
• Grant date: Feb 6, 2001
• Expiry date: Mar 30, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C405/0025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed is the use of cloprostenol and fluprostenol analogues and combinations thereof with other medicaments for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor. Also disclosed are methods of treating optic nerve disorders using the cloprostenol and fluprostenol analogues.