Process for the selective alkylation of aldehydes by means of organozinc compounds

US6184404A · kind A · utility

Assignee

• Metallgesellschaft AG · DE

Inventors

• Paul Knochel · Marburg, DE
• Christian Lutz · Kassel, DE

Key dates

• Filing date: Mar 1, 1999
• Grant date: Feb 6, 2001
• Expiry date: Mar 1, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There is described a process for the enantioselective alkylation of aldehydes by means of organozinc compounds, of which a ligand of the zinc is transferred to the aldehyde, and the other ligand acts as so-called dummy ligand. As novel substances there are used zinc-organic compounds, which contain the neophyl residue as dummy ligand.