Engineered acarid allergen and process for producing the same
US6187311A · kind A · utility
9Cited by
4References
6Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 26, 1997 |
| Grant date | Feb 13, 2001 |
| Priority date | — |
| Expiry date | Sep 26, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method for producing a modified major mite allergen, obtained by altering a major allergen of house dust mites by gene engineering, which involve the steps of culturing prokaryotic or eukaryotic host cells transformed with a replication vector containing a gene encoding modified major mite allergen expressed from a promoter and collecting the expressed modified major mite allergen from the culture. The present invention provides a modified major mite allergen produced by the method, DNA molecules encoding same, and a pharmaceutical composition containing the modified major mite allergen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.