Controlled release delivery of peptide or protein
US6187330A · kind A · utility
75Cited by
2References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 28, 1999 |
| Grant date | Feb 13, 2001 |
| Priority date | — |
| Expiry date | Jan 28, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/204
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and devices for the controlled release delivery of a peptide or protein drug are produced by dispersing a glassy matrix phase comprising the peptide or protein drug and a thermoprotectant in a bioerodable, biocompatible polymer at a temperature that is below the glass transition temperature of the glassy matrix phase and above the melting point of the polymer. The method and composition of the invention may be employed for the local delivery of angiogenic amounts of basic fibroblast growth factor or vascular endothelial growth factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.