Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
US6187335A · kind A · utility
17Cited by
11References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 31, 1997 |
| Grant date | Feb 13, 2001 |
| Priority date | — |
| Expiry date | Dec 31, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC11C3/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to an oral drug delivery system which delivers biologically active substances to the mucosal tissue of the intestine utilizing novel polymerized liposomes. Novel polymerizable fatty acids having a polymerizable group, a surfactant group, and a functional group, and optionally coupled to ligands which target mucosal tissue in the intestine are disclosed. Novel negatively charged polymerizable lipids which have phosphatidyl inositol (PI), phosphatidyl glycerol (PG) or phosphatidyl serine (PS) groups on a polymerizable backbone are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.