Patent · US Expired

Methods and reagents for in situ amplification

US6187567A · kind A · utility

4Cited by
8References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 1, 1999
Grant dateFeb 13, 2001
Priority date
Expiry dateSep 1, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6841
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides in situ amplification methods for the detection of a target nucleic acid molecule. The methods use a molecule termed "molecular tape" to retain the amplified target nucleic acid molecule within a cell upon amplification. The molecular tape, which may be used with a variety of amplification methods, improves the in situ detection of an amplified target molecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.