Process for producing optically active amines
US6187582A · kind A · utility
2Cited by
8References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 20, 1998 |
| Grant date | Feb 13, 2001 |
| Priority date | — |
| Expiry date | Nov 20, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01K7/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a novel process for producing known optically active amines and optically active acylated amines by: PA1 a) in a first step, reacting racemic amines with esters, in the presence of hydrolases and possibly a diluent; PA1 b) in a second step, separating the reaction mixture into (S)-amine and acylated (R)-amine; and c) optionally in a third step releasing (R)-amine from acylated PA1 (R)-amine by treatment with an acid or base, possibly in the presence of a diluent. The optically active amines can be employed as intermediates for preparing pharmaceuticals and crop protection agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.