Method for healing and repair of connective tissue attachment
US6187742A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 23, 1999 |
| Grant date | Feb 13, 2001 |
| Priority date | — |
| Expiry date | Mar 23, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for the treatment of defects and disease involving the functional attachment of connective tissue, such as tendon or ligament, to bone. Preferred methods comprise administering a composition containing a bone morphogenetic protein and a suitable carrier. The method results in the regeneration of functional attachment between the connective tissue and bone, such that minimal fibrous or granulation tissue is formed at the interface between the regenerated bone and connective tissue. The method and composition are useful for augmenting tissue grafts in reconstructive surgery. The method and compositions result in closer apposition of bone to the connective tissue at earlier time points and increased strength of fixation at earlier time points.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.