Benzoxazepine derivatives and their salts and medicaments containing the same
US6187769A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 7, 1999 |
| Grant date | Feb 13, 2001 |
| Priority date | — |
| Expiry date | May 7, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A benzoxazepine derivative having the general formula (I) and its salts and medicaments containing the same as effective ingredients: ##STR1## wherein, n is an integer of 2 to 5, R.sup.1 indicates a hydrogen atom, halogen atom, C.sub.1 to C.sub.4 lower alkyl group, C.sub.1 to C.sub.4 lower alkoxyalkyl group, C.sub.1 to C.sub.4 halogenoalkyl group, cyano group, or ester group, R.sup.2 indicates a hydrogen atom, halogen atom, C.sub.1 to C.sub.4 lower alkyl group, C.sub.1 to C.sub.4 lower alkoxy group, or hydroxy group, a dotted line indicates the presence or absence of a binding bond, W indicates C, CH, or CH.sub.2 or a nitrogen atom, provided that, when W is a nitrogen atom, Z is bonded to W and the dotted line indicates the absence of a bond, and Z indicates an unsubstituted or substituted aromatic hydrocarbon ring group or an unsubstituted or substituted heterocyclic group). This benzoxazepine derivative and its salts are useful as medicaments for the treatment of anxiety neurosis, phobias, obsessive-compulsive disorders, schizophrenia, post-cardiac trauma stress, depression, psychosomatic and other psychoneurotic disorders, eating disorders, menopausal disorders, infantile autism…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.