Sustained/immediate acting ketoprofen patch and process for manufacturing the same
US6190690A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 27, 1997 |
| Grant date | Feb 20, 2001 |
| Priority date | — |
| Expiry date | Jun 27, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/608
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained/immediate acting ketoprofen patch. A moisture permeable backing, a moisture non-permeable primer, a moisture high-permeable drug layer containing ketoprofen and a skin adhesion layer controlling release of a drug solution are piled up. An ethyl acetate soluble acrylic/rubber adhesive is coated onto a silicon coated paper, dried and transfer coated onto the backing to form the primer. The drug layer is formed by coating a drug solution onto a silicon coated paper, drying and transfer coating onto the primer. The skin adhesion layer is formed by coating a mixture of a solution prepared by dissolving an emulsifier in ethyl acetate and acrylic adhesive, drying and transfer coating onto the drug layer. The ketoprofen patch has a drug release controlling function and a good adhesion strength. The drug transferring effect through the skin is good.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.