Method of incorporating proteins or peptides into a matrix and administration thereof through mucosa
US6190699A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 8, 1998 |
| Grant date | Feb 20, 2001 |
| Priority date | — |
| Expiry date | May 8, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1652
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a surprising new and effective pharmaceutical composition comprising microparticles and a pharmaceutically acceptable carrier. In particular, the present invention describes a pharmaceutical composition containing microparticles off a matrix material into which is infused a therapeutic agent. The present invention further provides a method of infusing a therapeutic agent such as a protein or peptide into a matrix material to form microparticles containing said therapeutic agent by employing a compressed solvent which is normally gaseous at ambient temperature and pressure. A method is also disclosed of treating or preventing a disease in a mammal by administering to said mammal through a mucosal membrane an effective amount of a pharmaceutical composition comprising microparticles containing a therapeutic agent which effectively treats the disease or disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.