Patent · US Expired

Recombinant factor VIII binding peptides

US6191256A · kind A · utility

2Cited by

2References

3Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Li Chen · Hsinchu, TW
Joseph A. Buettner · Raleigh, US
Ruben G. Carbonell · Raleigh, US

Key dates

Filing date	Nov 20, 1998
Grant date	Feb 20, 2001
Priority date	—
Expiry date	Nov 20, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/755
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Peptides that have domains that bind to recombinant factor VIII (rFVIII) are disclosed. A method of rFVIII binding assay using the peptides deduced from a combinatorial library in a filtration plate process is described. A method of using peptides having these available binding domains in an affinity chromatography process to purify factor VIII is also taught.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.