Water-soluble rhodamine dyes and conjugates thereof
US6191278A · kind A · utility
79Cited by
8References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 3, 1999 |
| Grant date | Feb 20, 2001 |
| Priority date | — |
| Expiry date | Nov 3, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2458/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides novel, water-soluble, red-emitting fluorescent rhodamine dyes and red-emitting fluorescent energy-transfer dye pairs, as well as labeled conjugates comprising the same and methods for their use. The dyes, energy-transfer dye pairs and labeled conjugates are useful in a variety of aqueous-based applications, particularly in assays involving staining of cells, protein binding, and/or analysis of nucleic acids, such as hybridization assays and nucleic acid sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.