Patent · US Expired

Septicemia prevention and treatment system

US6193681A · kind A · utility

37Cited by
11References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 14, 1998
Grant dateFeb 27, 2001
Priority date
Expiry dateSep 14, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2205/75
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A method and apparatus for preventing and treating septicemia in patient blood. The extracorporeal system includes an anti-microbial device to kill at least 99% of bloodborne microorganisms, a hemoconcentrator/filtration unit to remove approximately 90% of target molecules from the patient blood and a filter unit to remove target molecules from patient blood from the sieved plasma filtrate. Target molecules are produced by microorganisms as well as the patient's cells and include endotoxins from gram negative bacteria, exotoxins from gram negative and gram positive bacteria, as well as RAP protein mediator from Staphylococcus aureus, and cell mediators such as tumor necrosis factor-alpha, and interleukin 1-beta, complement proteins C3a and C5a, and brandykinin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.