Methods for using anti-.alpha.v.beta.3 integrin antibody

US6193968A · kind A · utility

Assignees

• The Burnham Institute · US
• G.D. Searle LLC · US

Inventors

• Christopher P. Carron · Wildwood, US
• Debra M. Meyer · Wentzville, US
• George A. Nickols · Wentzville, US
• Jeffrey W. Smith · Elkton, US

Key dates

• Filing date: Apr 9, 1998
• Grant date: Feb 27, 2001
• Expiry date: Apr 9, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Monoclonal antibodies that recognize the .alpha..sub.v.beta..sub.3 integrin receptor complex, but do not significantly bind to .alpha..sub.IIb.beta..sub.IIIa, can be used in methods for treating .alpha..sub.v.beta..sub.3 integrin-mediated diseases, such as tunor metastasis.