Malignant human cell transformation detection method
US6194154A · kind A · utility
0Cited by
0References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 4, 1998 |
| Grant date | Feb 27, 2001 |
| Priority date | — |
| Expiry date | Sep 4, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for detecting malignant transformation of cells involves detecting the overexpression of the products of the .beta.3, .beta.5, .beta.8 and .beta.9 genes, which encode the hCG.beta. subunit, relative to their expression in nonmalignant cells. A kit for diagnosing an hCG- or an hCG fragment-secreting cancer includes an assembly of polypeptides covering at least a part of the primary sequence of hCG. The use of a polypeptide corresponding to at least one portion of the primary sequence of hCG for producing a composition useful in hCG- or hCG fragment-secreting cancer immunotherapy is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.