Apoptosis-inducing protein and gene encoding the same
US6194187A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1998 |
| Grant date | Feb 27, 2001 |
| Priority date | — |
| Expiry date | Oct 19, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An object of the present invention is to provide a protein which induces apoptosis, a base sequence encoding the protein, and an agent for use in the treatment of malignant tumors. The present invention is a protein (ASK1) which has protein kinase activity and enhances SEK1 kinase activity and/or MKK3 kinase activity, or a derivative thereof. Malignant tumors can be treated using the protein according to the present invention or the base sequence encoding the protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.