Patent · US Expired

Apoptosis-inducing protein and gene encoding the same

US6194187A · kind A · utility

2Cited by
0References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 19, 1998
Grant dateFeb 27, 2001
Priority date
Expiry dateOct 19, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K48/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An object of the present invention is to provide a protein which induces apoptosis, a base sequence encoding the protein, and an agent for use in the treatment of malignant tumors. The present invention is a protein (ASK1) which has protein kinase activity and enhances SEK1 kinase activity and/or MKK3 kinase activity, or a derivative thereof. Malignant tumors can be treated using the protein according to the present invention or the base sequence encoding the protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.