Patent · US Expired

Transcriptional regulatory sequence of carcinoembryonic antigen for expression targeting

US6194211A · kind A · utility

18Cited by
1References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 16, 1996
Grant dateFeb 27, 2001
Priority date
Expiry dateMay 16, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/85
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The transcriptional regulatory sequence (TRS) of Carcinoembryonic Antigen (CEA) and molecular chimeras comprising the CEA TRS and DNA encoding a heterologous enzyme are described. Such molecular chimeras are capable of targeting the expression of the heterologous enzyme to CEA-positive cells. The heterologous enzyme may be cytosine deaminase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.