Lipophilic, functionalized nanocrystals and their use for fluorescence labeling of membranes
US6194213A · kind A · utility
25Cited by
3References
21Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 10, 1999 |
| Grant date | Feb 27, 2001 |
| Priority date | — |
| Expiry date | Dec 10, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided is a method of fluorescence detection of lipid membranes using lipophilic, functionalized nanocrystals; and lipid membranes labeled by the lipophilic, functionalized nanocrystals. The method comprises contacting an effective amount of lipophilic, functionalized nanocrystals with the lipid membranes; exposing the labeled lipid membranes to an excitation light suitable for exciting the functionalized nanocrystals present in the labeled lipid membranes to emit a fluorescence emission. Also provided is a composition comprising a functionalized nanocrystal which is bound to a substrate in a living tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.