Patent · US Expired

Phosphonate nucleotide compound

US6194398A · kind A · utility

5Cited by
0References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 17, 1999
Grant dateFeb 27, 2001
Priority date
Expiry dateJun 17, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A phosphonate nucleotide compound represented by formula (I): ##STR1## (wherein R.sup.1 is a C.sub.1 -C.sub.6 alkyl group or the like, R.sup.2 is a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group substituted by one or more halogen atoms or the like, R.sup.3 is a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group substituted by one or more halogen atoms or the like, R.sup.4 is a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group substituted by one or more halogen atoms and X is a carbon atom or a nitrogen atom), a salt thereof, a hydrate thereof or a solvate thereof, as well as a medicament containing the same. It is useful as an antiviral agent for human immunodeficiency virus, herpes simplex virus, hepatitis B virus or the like and as an antitumor agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.