Process for the isolation of galanthamine

US6194404A · kind A · utility

Assignee

• LTS Lohmann Therapie-Systeme AG · DE

Inventors

• Thomas Hille · Neuwied, DE
• Hans-Rainer Hoffmann · Neuwied, DE
• Mirko Kreh · Marburg, DE
• Rudolf Matusch · Marburg, DE

Key dates

• Filing date: Aug 7, 1998
• Grant date: Feb 27, 2001
• Expiry date: Aug 7, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P39/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.