Imidazonaphthyridines

US6194425A · kind A · utility

Assignee

• 3M INNOVATIVE PROPERTIES COMPANY · US

Inventors

• John F. Gerster · Woodbury, US
• Kyle J. Lindstrom · Houlton, US
• Stephen L. Crooks · Mahtomedi, US
• Philip D. Heppner · Woodbury, US
• Gregory J. Marszalek · Windom, US
• Peter Maye · Windom, US
• Bryon A. Merrill · River Falls, US
• John Mickelson · Mattawan, US
• Michael J. Rice · Oakdale, US

Key dates

• Filing date: Dec 11, 1998
• Grant date: Feb 27, 2001
• Expiry date: Dec 11, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.