Polyaromatic heterocyclic compounds and pharmaceutical compositions comprised thereof

US6194450A · kind A · utility

Assignee

• Centre International de Recherches Dermatalogiques Galderma (C.I.R.D.) Galderma · FR

Inventors

• Bruno Charpentier · Biot, FR
• Philippe Diaz · Nice, FR
• Philippe Nedoncelle · Grasse, FR

Key dates

• Filing date: Jul 23, 1998
• Grant date: Feb 27, 2001
• Expiry date: Jul 23, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q19/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): ##STR1## in which Z is a divalent radical selected from among --O--, --S-- or --Nr'-- and Ar is either a radical having the following structural formula (II): ##STR2## or a radical having the following structural formula (III): ##STR3## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.