Process for preparing 5-lipoxygenase inhibitors
US6194585A · kind A · utility
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25Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 24, 1999 |
| Grant date | Feb 27, 2001 |
| Priority date | — |
| Expiry date | Aug 24, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D249/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to the process for preparing a compound of the formula ##STR1## PA1 wherein A is C.sub.1 -C.sub.6 alkyl, an aryl which is mono or disubstituted with F, Cl, Br, OCH.sub.3, C.sub.1 -C.sub.3 alkyl or benzy. In the preferred compound A is CH.sub.3. The 5-lipoxygenase inhibitors that are prepared in accordance with the present invention are selective inhibitors of the action of lipoxygenase enzyme and are useful in the treatment or alleviation of inflammatory diseases, allergy and cardiovascular diseases in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.