Process for preparing biaryl compounds
US6194599A · kind A · utility
16Cited by
10References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 8, 1997 |
| Grant date | Feb 27, 2001 |
| Priority date | — |
| Expiry date | Apr 8, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C253/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a process for preparing biaryl compounds comprising reacting an arylzinc reagent with an arylchloride in the presence of a nickel catalyst or a palladium catalyst. The present invention specifically provides a process for the preparation of 2-(4'-methylphenyl)benzonitrile comprising reacting a 4-methylphenylzinc reagent with 2-chlorobenzonitrile in the presence of a nickel catalyst or a palladium catalyst.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.