Patent · US Expired

Supplemented and unsupplemented tissue sealants, methods of their production and use

US6197325A · kind A · utility

429Cited by
56References
48Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateMar 6, 2001
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S623/915
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides methods for the localized delivery of supplemented tissue sealants, wherein the supplemented tissue sealants comprise at least one composition which is selected from one or more antibodies, analgesics, anticoagulants, anti-inflammatory compounds, antimicrobial compositions, antiproliferatives, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like. Further provided are methods of using the site-specific supplemented tissue sealants, including preparation of a biomaterial.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.