Method of analyzing DNA using contiguous repeats
US6197509A · kind A · utility
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17Claims
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Key dates
| Filing date | May 13, 1999 |
| Grant date | Mar 6, 2001 |
| Priority date | — |
| Expiry date | May 13, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel, highly polymorphic DNA marker based on the pentanucleotide repeat (CCTTT/GGAAA).sub.n has been identified in the human inducible nitric oxide synthase (iNOS) gene. Twelve different alleles, having between 7 and 18 repeats, have been identified. The repeat is highly polymorphic in the human population and so lends itself to use as a microsatellite marker with uses in, for example, forensic medicine, population studies, family linkage studies and disease diagnosis.
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