Patent · US Expired

PNA and DNA conjugates and methods for preparation thereof

US6197513A · kind A · utility

14Cited by
1References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 10, 1999
Grant dateMar 6, 2001
Priority date—
Expiry dateFeb 10, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/003
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed herein are methods for linking a protein or other biomolecule containing a carboxylic acid moiety to a PNA or DNA probe molecule. The methods disclosed herein involve activating the carboxylic acid moiety with an activating agent and reacting the activated carboxylic acid moiety with a PNA or DNA probe having an arylamine or aminooxyacetyl moiety. Conjugates produced by these methods are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.