Patent · US Expired

Trigger factor expression plasmids

US6197547A · kind A · utility

2Cited by

0References

25Claims

0Family size

Assignee

HSP Research Institute, Inc. · JP

Inventors

Kazuyo Sogo · Kyoto, JP
Hideki Yanagi · Tochigi, JP
Takashi Yura · Kyoto, JP

Key dates

Filing date	Dec 28, 1999
Grant date	Mar 6, 2001
Priority date	—
Expiry date	Dec 28, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/78
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

An artificial operon comprising genes encoding each of a trigger factor, GroEL and GroES, an expression plasmid carrying the operon, an expression plasmid carrying a gene encoding the trigger factor, a cotransformant harboring an expression vector for a foreign protein and any one of the expression plasmids, and a method for producing a foreign protein comprising expressing a foreign protein by the use of the cotransformant, which are capable of expressing a foreign protein in a solubilized form and in a state of having a correct conformation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.