Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives

US6197812A · kind A · utility

Assignee

• Alcon Laboratories, Inc. · US

Inventors

• Robert Selliah · Fort Worth, US
• Mark R. Hellberg · Arlington, US
• Peter G. Klimko · Fort Worth, US
• Verney L. Sallee · Burleson, US
• Paul W. Zinke · Fort Worth, US

Key dates

• Filing date: Nov 15, 1999
• Grant date: Mar 6, 2001
• Expiry date: Nov 15, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D493/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.