Antagonists of gonadotropin releasing hormone

US6197975A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Mark Goulet · Westfield, US
• Wallace T. Ashton · Edison, US
• Lin Chu · Scotch Plains, US
• Michael H. Fisher · Bound Brook, US
• Matthew J. Wyvratt · Mountainside, US

Key dates

• Filing date: Jun 1, 1998
• Grant date: Mar 6, 2001
• Expiry date: Jun 1, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are disclosed compounds of formula (I) and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women. ##STR1##