Measuring device and its use

US6198869A · kind A · utility

Assignee

• Novartis AG · CH

Inventors

• Gerolf Kraus · Kandern, DE
• Michael Pawlak · Laufenbürg, DE
• Gert Ludwig Duveneck · Bad Krozingen, DE
• Peter Oroszlan · Basel, CH
• Andreas Helg · Möhlin, CH
• Alfredo Emilio Bruno-Raimondi · Biel-Benken, CH

Key dates

• Filing date: May 17, 1999
• Grant date: Mar 6, 2001
• Expiry date: May 17, 2019

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/0346
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A device comprising a planar optical waveguide, consisting of a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer, and there is located on the wave-guiding layer a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inflow channel (2) and an outflow channel (3), the depth of the cavity corresponding at least to the penetration depth of the evanescent field, and wherein the diffractive element (42) is fully covered by the material of the layer (43) at least in the coupling-in region of the excitation radiation.