Patent · US Expired

Biological implants of semipermeable amphiphilic membranes

US6200589A · kind A · utility

43Cited by
14References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 1998
Grant dateMar 13, 2001
Priority date
Expiry dateFeb 27, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L31/048
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An implantable biological device including a semipermeable membrane formed into a geometric shape capable of encapsulating biological cells and capable of immunoisolating the biological cells upon introduction into the body, the semipermeable membrane including an amphiphilic copolymer network having hydrophobic segments and hydrophilic segments, wherein the hydrophobic segments include polyolefins terminated with radicals selected from the group consisting of acryloyl groups, methacryloyl groups and mixtures thereof and wherein the hydrophilic segments include polyacrylates. Also provided is a method of encapsulating and immunoisolating cells using the semipermeable membrane and method of treating ailments using the implantable biological device.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.