Formulation and use of carotenoids in treatment of cancer
US6200597A · kind A · utility
7Cited by
19References
6Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 10, 1998 |
| Grant date | Mar 13, 2001 |
| Priority date | — |
| Expiry date | Jun 10, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/127
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A reduced-toxicity formulation of carotenoids is disclosed which is stable in an aqueous environment. The formulation includes a carotenoid, lipid arrier particles (such as liposomes), and an intercalation promoter agent (such as a triglyceride), which causes the carotenoid to be substantially uniformly distributed with the lipid in the lipid carrier particles. The molar ratio of carotenoid to lipid is greater than about 1:10. Also disclosed is a method of inhibiting the growth of cancer cells, which comprises administering to a living subject a therapeutically effective amount of a composition as described above.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.