Process for the preparation of nootkatone by laccase catalysis
US6200786A · kind A · utility
13Cited by
2References
38Claims
0Family size
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Key dates
| Filing date | Sep 8, 1999 |
| Grant date | Mar 13, 2001 |
| Priority date | — |
| Expiry date | Sep 8, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing nootkatone by laccase catalyzed oxidation of valencene. Valencene and a composition having laccase activity are reacted in the presence of an oxygen source, at a valencene concentration greater than 0.1%, to form valencene hydroperoxide. Optionally, a mediator and/or a solvent at a concentration that maintains laccase activity may also be included. The valencene hydroperoxide is degraded to form nootkatone, and nootkatone is then recovered. The method produces nootkatone in commercially viable yields.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.