Antagonists of gonadotropin releasing hormone

US6200957A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Mark Goulet · Westfield, US
• Wallace T. Ashton · Edison, US
• Lin Chu · Scotch Plains, US
• Michael H. Fisher · Bound Brook, US
• Peter Lin · Luzhu District, TW
• Mitree M. Ponpipom · Readington, US
• Matthew J. Wyvratt · Mountainside, US
• Narindar N. Girotra · Old Bridge, US
• Jonathan R. Young · Southborough, US

Key dates

• Filing date: Jul 14, 1998
• Grant date: Mar 13, 2001
• Expiry date: Jul 14, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.